DARTNet Institute Informing Practice Improving Care
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Cardiovascular Risk Reduction Learning Community (CRRLC)

The goals of this project are:

  1. Form a Cardiovascular Risk Reduction Learning Community;
  2. Electronically collect and analyze data on trajectories of hypertension and LDL-cholesterol control, antihypertensive and hypolipidemic drug prescription and fulfillment data, and relatively mutable and relatively immutable factors associated with hypertension and LDL control;
  3. Develop a system for electronic feedback of aggregate data to compare clinic performance and of patient-level data to assist care providers in focusing their efforts in improving blood pressure and LDL control; and
  4. Assess incidence and changes in blood pressure and LDL control before and after implementation of feedback to calculate sample size for a randomized controlled trial.

1. Translation of the JNC7 and NCEP guidelines into electronic algorithms for use of data electronically extracted, transformed, and loaded from the EHR suitable to produce patient-specific, point of care decision support and audit with feedback for both timeliness of measurement and control of blood pressure and LDL.

2. Modification of Wilson Pace’s aggregation of individual ICD-9 codes into comorbidity clusters for use in risk-adjustment of blood pressure and LDL timeliness of measurement and non-control


Risk-adjusted comparison of blood pressure and low-density lipoprotein (LDL) noncontrol in primary care offices.
Hammermeister K, Bronsert M, Henderson WG, Coombs L, Hosokawa P, Brandt E, Bryan C, Valuck R, West D, Liaw W, Ho M, Pace W.
J Am Board Fam Med. 2013 Nov-Dec;26(6):658-68. doi: 10.3122/jabfm.2013.06.130017.
Abstract  | Full Text 

Comparative effectiveness of antihypertensive therapeutic classes and treatment strategies in the initiation of therapy in primary care patients: a Distributed Ambulatory Research in Therapeutics Network (DARTNet) study.
Bronsert MR, Henderson WG, Valuck R, Hosokawa P, Hammermeister K.
J Am Board Fam Med. 2013 Sep-Oct;26(5):529-38. doi: 10.3122/jabfm.2013.05.130048.
Abstract   | Full Text   


A Cardiovascular Risk Reduction Learning Community in DARTNet, Karl Hammermeister, University of Colorado School of Medicine, NHLBI 1RC1HL101071-01, $499,926

Dataset Description

Type of Patients Included N Data Elements
All patients over 18 964968
  • C-reactive protein (CRP)
  • Gender
  • Systolic blood pressure
  • Diastolic blood pressure
  • Height
  • Weight
  • Hemoglobin A1c
  • ALT (alanine aminotransferase)
  • AST (aspartate aminotransferase)
  • Total cholesterol
  • HDL cholesterol
  • LDL cholesterol
  • Year of birth
  • Serum creatinine
  • Encounters
  • Glucose level (fasting)
  • Glucose level (non-fasting)
  • Total bilirubin
  • INR (International Standardized Ratio)
  • Platelet count
  • Diagnoses
  • Smoking Status
  • Drinking Status
  • Premature onset of CVD in first degree relative
  • Medication Allergies
  • Medications Prescribed
  • Medication Fulfillment Data
  • Serum triglycerides